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This presents us with a question: In a fast-changing world, is there a way to govern human behavior that proactively embraces change Despite Winston Churchill s quip that democracy is the worst system of government except all the others, it does work. But it works as a social contract because democratic countries are not founded on a set of rules, but rather on a set of shared values, on constitutions. Constitutions are powerful documents because they are lled with the values and principles of the people they govern, such as free expression, liberty, enfranchisement, fairness, justice, the pursuit of happiness, or the rule of law. These core, foundational values can be interpreted and reapplied to new situations as they arise. The more profound the document, the more durably it can adapt to changing times. The key to long-term, sustained success does not lie in breaking all the rules; it lies in transcending the rules and harnessing the power of values.

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Content delivery techniques for the wireline Internet can be roughly categorized into three areas: network scaling, which improves the scalability of the network by distributing content to multiple servers; end-system acceleration, which speeds up the content delivery at content source and destination; and content and protocol optimization, which improves content transmission ef ciency. This taxonomy is

TABLE 7.2 Proposed Tobacco and Nicotine Phenotype Classi cation System Phenotype Class I Characteristics Relatively crude, broad summary or cross-sectional measures of smoking behavior, such as ever/never-smoker, current/former/never-smoker, age at smoking initiation, and average number of cigarettes smoked per day. The majority of genetic studies, to date, have involved only this level of phenotypic description. Measures or indicators of tobacco dependence, such as the Fagerstr m Tolerance Questionnaire and its more recent variant, the Fagerstr m Test for Nicotine Dependence, time to rst cigarette in the morning, and number of quit attempts, or psychiatric-type classi cations based on the DSM IV system. Longitudinal assessments that emphasize the process of, or progression toward the development of regular smoking or tobacco dependence. Although class III phenotypes can be summarized to create a class I or II phenotype, class III is differentiated by the nature of the data, whereby class III retains its longitudinal properties and is presented as a trajectory. As an illustration, two individuals both might be classi ed as ever-smokers, having smoked 100 or more cigarettes in their life, yet their smoking topography may differ dramatically for example, one person might have taken years to develop into a daily smoker, whereas the other might have converged rapidly on daily smoking (and thus have a much steeper slope or trajectory for the development of daily smoking). Nicotine pharmacokinetic parameters (the effects of the body on the drug, i.e., nicotine absorption, distribution, metabolism, and excretion rates; and pharmaco-dynamic effects (the effects of the drug on the body, including physiologic responses such as mood alteration, heightened concentration, and changes in receptor function and density).

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Machine B Discount Factor 0.9091 0.8264 0.7513 0.6830 0.6209 Present Value $ 2,061 3,609 3,018 2,983 2,836 $14,507 ( 9,400) $ 5,107

defensiveness Twenty percent of patients who were initially found to be highly defensive had developed hypertension, while only 45% of those with low defensiveness developed the condition Statistical adjustment for many general risk factors (including smoking, exercise levels, alcohol consumption, and body fat) revealed that membership in the highly defensive group was associated with more than a sevenfold risk of developing hypertension over the threeyear period Various researchers differ in their views of the association between personality trait differences/emotions and hypertension Early investigators (Alexander, 1939; Dunbar, 1943) and some more recent researchers (Jern, 1987) have hypothesized a causal role for personality traits in the development of hypertension Some researchers (Esler et al, 1977; Weder & Julius, 1987) have postulated mechanisms by which certain personality traits elicit excessive central and sympathetic nervous system arousal, predisposing one to hypertension.

*NSF refers to a deposited check that was not cashed due to insufficient funds in the account of the maker.